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2025

Unit Publication
Cagnan H
Denison T

Patent Application: Systems and methods for generating a stimulation signal for brain or nerve stimulation and for performing brain or nerve stimulation

WO/2025/022112
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2.12 MB
Unit Publication
West TO
Steidel K
Flessner T
Calvano A
Kucukahmetler D
Stam MJ
Spedden ME
Wahl B
Jousmäki V
Eraifej J
Oswal A
Saifee TA
Barnes G
Farmer SF
Pedrosa D
Cagnan H

Essential tremor disrupts rhythmic brain networks during naturalistic movement.

2025. Neurobiol Dis, 207:106858.

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PMC7617547
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3.13 MB
Unit Publication
Härmson O
Grennan I
Perry B
Toth R
McNamara CG
Denison T
Cagnan H
Manohar S
Walton ME
Sharott A

Multi-level encoding of reward, effort, and choice across the frontal cortex and basal ganglia during cost-benefit decision-making.

2025. Cell Rep, 44(2):115209.

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PMC11860760
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6.63 MB

2024

Unit Publication
He S
West TO
Plazas FR
Wehmeyer L
Pogosyan A
Deli A
Wiest C
Herz DM
Simpson TG
Andrade P
Baig F
Hart MG
Morgante F
Fitzgerald J
Barbe MT
Visser-Vandewalle V
Green AL
Pereira EA
Cagnan H
Tan H

Cortico-thalamic tremor circuits and their associations with deep brain stimulation effects in essential tremor.

2024. Brain (e-Pub ahead of print).

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1.31 MB
Unit Publication
Grennan I
Mallet N
Magill PJ
Cagnan H
Sharott A

Beta bursts in the parkinsonian cortico-basal ganglia network form spatially discrete ensembles.

2024. Neurobiol Dis, 201:106652.

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PMC11496931
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9.4 MB
Unit Publication
Mandali A
Torrecillos F
Wiest C
Pogosyan A
He S
Soriano DC
Tan H
Stagg CJ
Cagnan H

Tuning the brakes - Modulatory role of transcranial random noise stimulation on inhibition.

2024. Brain Stimul, 17(2):392-394.

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PMC7616112
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1.24 MB

2023

Unit Publication
Fleming JE
Pont Sanchis I
Lemmens O
Denison-Smith A
West TO
Denison T
Cagnan H

From dawn till dusk: Time-adaptive bayesian optimization for neurostimulation.

2023. PLoS Comput Biol, 19(12)e1011674.

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PMC10718444
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2.94 MB
Unit Publication
West TO
Duchet B
Farmer SF
Friston KJ
Cagnan H

When do bursts matter in the primary motor cortex? Investigating changes in the intermittencies of beta rhythms associated with movement states.

2023. Prog Neurobiol, 221:102397.

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PMC7614511
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7.42 MB

2022

Unit Publication
West TO
Magill PJ
Sharott A
Litvak V
Farmer SF
Cagnan H

Stimulating at the right time to recover network states in a model of the cortico-basal ganglia-thalamic circuit.

2022. PLoS Comput Biol, 18(3)e1009887.

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PMC8939795
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3.33 MB

2021

Unit Publication
Arruda BS
Reis C
Sermon JJ
Pogosyan A
Brown P
Cagnan H

Identifying and modulating distinct tremor states through peripheral nerve stimulation in Parkinsonian rest tremor.

2021. J Neuroeng Rehabil, 18(1):179.

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PMC8709974
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2.4 MB
Unit Publication
Reis C
Arruda BS
Pogosyan A
Brown P
Cagnan H

Essential tremor amplitude modulation by median nerve stimulation.

2021. Sci Rep, 11(1):17720.

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PMC8421420
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1.59 MB

2020

Unit Publication
Fischer P
He S
de Roquemaurel A
Akram H
Foltynie T
Limousin P
Zrinzo L
Hyam J
Cagnan H
Brown P
Tan H

Entraining stepping movements of Parkinson's patients to alternating subthalamic nucleus deep brain stimulation.

2020. J. Neurosci., 40(46):8964–8972.
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PMC7659462
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1017.91 KB
Unit Publication
Duchet B
Weerasinghe G
Cagnan H
Brown P
Bick C
Bogacz R

Phase-dependence of response curves to deep brain stimulation and their relationship: from essential tremor patient data to a Wilson-Cowan model.

2020. J. Math. Neurosci., 10(1):4.
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PMC7105566
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4.54 MB

2019

Unit Publication
Cagnan H
Denison T
McIntyre C
Brown P

Emerging technologies for improved deep brain stimulation.

2019. Nat. Biotechnol., 37(9):1024-1033.
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PMC6877347
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2.75 MB
Unit Publication
Weerasinghe G
Duchet B
Cagnan H
Brown P
Bick C
Bogacz R

Predicting the effects of deep brain stimulation using a reduced coupled oscillator model.

2019. PLoS Comput. Biol., 15(8):e1006575.
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PMC6701819
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2.63 MB
Unit Publication
Cagnan H
Mallet N
Moll CK
Gulberti A
Holt AB
Westphal M
Gerloff C
Engel AK
Hamel W
Magill PJ
Brown P
Sharott A

Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network.

2019. Proc. Natl. Acad. Sci. U.S.A., 116:16095-16104.
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PMC6690030
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1.59 MB
Unit Publication
Reis C
Sharott A
Magill PJ
van Wijk B
Parr T
Zeidman P
Friston KJ
Cagnan H

Thalamocortical dynamics underlying spontaneous transitions in beta power in Parkinsonism.

2019. Neuroimage, 193:103-114.
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PMC6503152
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1.35 MB
Unit Publication
Holt AB
Kormann E
Gulberti A
Pötter-Nerger M
McNamara CG
Cagnan H
Baaske MK
Little S
Köppen JA
Buhmann C
Westphal M
Gerloff C
Engel AK
Brown P
Hamel W
Moll CK
Sharott A

Phase-Dependent Suppression of Beta Oscillations in Parkinson's Disease Patients.

2019. J. Neurosci., 39(6):1119-1134.
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PMC6363933
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3.34 MB

2018

Unit Publication
Pedrosa D
Brown P
Cagnan H
Visser-Vandewalle V
Wirths J
Timmermann L
Brittain JS

A functional micro-electrode mapping of ventral thalamus in essential tremor.

2018.Brain, 141(9):2644-2654.
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PMC6113647
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827.88 KB

2017

Unit Publication
di Biase L
Brittain JS
Shah SA
Pedrosa D
Cagnan H
Mathy A
Chen CC
Martín-Rodríguez JF
Mir P
Timmermann L
Schwingenschuh P
Bhatia K
Di Lazzaro V
Brown P

Tremor stability index: a new tool for differential diagnosis in tremor syndromes.

2017.Brain, 140(7):1977-1986.
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PMC5493195
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565.63 KB
Unit Publication
Meidahl AC
Tinkhauser G
Herz DM
Cagnan H
Debarros J
Brown P

Adaptive Deep Brain Stimulation for Movement Disorders: The Long Road to Clinical Therapy.

2017.Mov. Disord., 32(6):810-819.

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PMC5482397
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647.98 KB
Unit Publication
Cagnan H
Pedrosa D
Little S
Pogosyan A
Cheeran B
Aziz TZ
Green AL
Fitzgerald J
Foltynie T
Limousin P
Zrinzo L
Hariz M
Friston KJ
Denison T
Brown P

Stimulating at the right time: phase-specific deep brain stimulation.

2017. Brain, 140(1):132-145.
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PMC5226063
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727.64 KB

2016

Unit Publication
Little S
Tripoliti E
Beudel M
Pogosyan A
Cagnan H
Herz DM
Bestmann S
Aziz TZ
Cheeran B
Zrinzo L
Hariz M
Hyam J
Limousin P
Foltynie T
Brown P

Adaptive deep brain stimulation for Parkinson's disease demonstrates reduced speech side effects compared to conventional stimulation in the acute setting.

2016.J. Neurol. Neurosurg. Psychiatry, 87(12):1388-1389.
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PMC5136720
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619.27 KB
Unit Publication
Little S
Beudel M
Zrinzo L
Foltynie T
Limousin P
Hariz M
Neal S
Cheeran B
Cagnan H
Gratwicke J
Aziz TZ
Pogosyan A
Brown P

Bilateral adaptive deep brain stimulation is effective in Parkinson's disease.

2016.J. Neurol. Neurosurg. Psychiatry, 87(7):717-21.
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PMC4941128
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651.81 KB

2015

Unit Publication
Cagnan H
Duff EP
Brown P

The relative phases of basal ganglia activities dynamically shape effective connectivity in Parkinson's disease.

2015.Brain, 138(Pt 6):1667-78.
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PMC4614137
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727.78 KB