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2023

Unit Publication
Herz DM
Bange M
Gonzalez-Escamilla G
Auer M
Muthuraman M
Glaser M
Bogacz R
Pogosyan A
Tan H
Groppa S
Brown P

Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior.

2023. PLoS Biol, 21(6)e3002140.

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PMC10234560
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2.88 MB
Unit Publication
Wiest C
Torrecillos F
Pogosyan A
Bange M
Muthuraman M
Groppa S
Hulse N
Hasegawa H
Ashkan K
Baig F
Morgante F
Pereira EA
Mallet N
Magill PJ
Brown P
Sharott A
Tan H

The aperiodic exponent of subthalamic field potentials reflects excitation/inhibition balance in Parkinsonism.

2023. eLife, 12:e82467

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PMC10005762
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1.17 MB
Unit Publication
Shah A
Nguyen TAK
Petermann K
Khawaldeh S
Debove I
Shah SA
Torrecillos F
Tan H
Pogosyan A
Lachenmayer ML
Michelis J
Brown P
Pollo C
Krack P
Nowacki A
Tinkhauser G

Combining Multimodal Biomarkers to Guide Deep Brain Stimulation Programming in Parkinson Disease.

2023. Neuromodulation, 26(2):320-332.

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PMC7614142
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2.07 MB

2021

Unit Publication
He S
Baig F
Mostofi A
Pogosyan A
Debarros J
Green AL
Aziz TZ
Pereira EA
Brown P
Tan H

Closed-Loop Deep Brain Stimulation for Essential Tremor Based on Thalamic Local Field Potentials.

2021. Mov Disord, 36(4):863-873.

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PMC7610625
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1.43 MB
Unit Publication
Wiest C
Tinkhauser G
Pogosyan A
He S
Baig F
Morgante F
Mostofi A
Pereira EA
Tan H
Brown P
Torrecillos F

Subthalamic deep brain stimulation induces finely-tuned gamma oscillations in the absence of levodopa.

2021. Neurobiol Dis, 152:105287.

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PMC7116781
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10.76 MB

2020

Unit Publication
He S
Mostofi A
Syed EC
Torrecillos F
Tinkhauser G
Fischer P
Pogosyan A
Hasegawa H
Li Y
Ashkan K
Pereira EA
Brown P
Tan H

Subthalamic beta-targeted neurofeedback speeds up movement initiation but increases tremor in Parkinsonian patients.

2020. eLife, 9:e60979.
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PMC7695453
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1.9 MB
Unit Publication
Wiest C
Tinkhauser G
Pogosyan A
Bange M
Muthuraman M
Groppa S
Baig F
Mostofi A
Pereira EA
Tan H
Brown P
Torrecillos F

Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease.

2020. Neurobiol. Dis., 143:105019.
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PMC7115855
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4.15 MB
Unit Publication
Tinkhauser G
Torrecillos F
Pogosyan A
Mostofi A
Bange M
Fischer P
Tan H
Hasegawa H
Glaser M
Muthuraman M
Groppa S
Ashkan K
Pereira EA
Brown P

The Cumulative Effect of Transient Synchrony States on Motor Performance in Parkinson's Disease.

2020. J. Neurosci., 40(7):1571-1580.

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PMC7044725
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1.35 MB

2019

Unit Publication
Fischer P
Pogosyan A
Green AL
Aziz TZ
Hyam J
Foltynie T
Limousin P
Zrinzo L
Samuel M
Ashkan K
Da Lio M
De Cecco M
Fornaser A
Brown P
Tan H

Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine.

2019. Neurobiol. Dis., 127:253-263.
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PMC6517271
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1.74 MB
Unit Publication
Tan H
Debarros J
He S
Pogosyan A
Aziz TZ
Huang Y
Wang S
Timmermann L
Visser-Vandewalle V
Pedrosa D
Green AL
Brown P

Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor.

2019. Brain Stimul., 12(4):858-867.
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PMC6600875
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2.18 MB

2018

Unit Publication
Tinkhauser G
Torrecillos F
Duclos Y
Tan H
Pogosyan A
Fischer P
Carron R
Welter ML
Karachi C
Vandenberghe W
Nuttin B
Witjas T
Régis J
Azulay JP
Eusebio A
Brown P

Beta burst coupling across the motor circuit in Parkinson's disease.

2018. Neurobiol. Dis., 117(Sept):217-225.
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PMC6054304
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1.23 MB
Unit Publication
Fischer P
Chen CC
Chang YJ
Yeh CH
Pogosyan A
Herz DM
Cheeran B
Green AL
Aziz TZ
Hyam J
Little S
Foltynie T
Limousin P
Zrinzo L
Hasegawa H
Samuel M
Ashkan K
Brown P
Tan H

Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping.

2018. J. Neurosci., 38(22):5111-5121.
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PMC5977446
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1.78 MB
Unit Publication
Tinkhauser G
Pogosyan A
Debove I
Nowacki A
Shah SA
Seidel K
Tan H
Brittain JS
Petermann K
di Biase L
Oertel M
Pollo C
Brown P
Schuepbach M

Directional local field potentials: A tool to optimize deep brain stimulation.

2018.Mov. Disord., 33(1):159-164.
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PMC5768242
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573.26 KB

2017

Unit Publication
Tinkhauser G
Pogosyan A
Tan H
Herz DM
Kühn AA
Brown P

Beta burst dynamics in Parkinson's disease OFF and ON dopaminergic medication.

2017. Brain, 140(11):2968-2981.
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PMC5667742
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998.05 KB
Unit Publication
Steiner LA
Neumann WJ
Staub-Bartelt F
Herz DM
Tan H
Pogosyan A
Kühn AA
Brown P

Subthalamic beta dynamics mirror Parkinsonian bradykinesia months after neurostimulator implantation.

2017.Mov. Disord., 32(8):1183-1190.

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PMC5575541
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423.21 KB
Unit Publication
Fischer P
Pogosyan A
Herz DM
Cheeran B
Green AL
Fitzgerald J
Aziz TZ
Hyam J
Little S
Foltynie T
Limousin P
Zrinzo L
Brown P
Tan H

Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition.

2017. eLife, 6:e23947
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PMC5526662
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2.83 MB
Unit Publication
Fischer P
Pogosyan A
Cheeran B
Green AL
Aziz TZ
Hyam J
Little S
Foltynie T
Limousin P
Zrinzo L
Hariz M
Samuel M
Ashkan K
Brown P
Tan H

Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force.

2017. Exp. Neurol., 293():53-61.
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PMC5429975
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1.7 MB
Unit Publication
Tinkhauser G
Pogosyan A
Little S
Beudel M
Herz DM
Tan H
Brown P

The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease.

2017. Brain, 140(4):1053-1067.
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PMC5382944
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928.26 KB

2016

Unit Publication
Fischer P
Tan H
Pogosyan A
Brown P

High post-movement parietal low-beta power during rhythmic tapping facilitates performance in a stop task.

2016.Eur. J. Neurosci., 44(5):2202-13.

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PMC5014120
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4.05 MB
Unit Publication
Tan H
Pogosyan A
Ashkan K
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Hariz M
Brown P

Decoding gripping force based on local field potentials recorded from subthalamic nucleus in humans.

2016. eLife;5:e19089.
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PMC5148608
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10.08 MB
Unit Publication
Guerra A
Pogosyan A
Nowak M
Tan H
Ferreri F
Di Lazzaro V
Brown P

Phase Dependency of the Human Primary Motor Cortex and Cholinergic Inhibition Cancelation During Beta tACS.

2016.Cereb. Cortex, 26(10):3977-90.

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PMC5028010
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727.73 KB

2015

Unit Publication
Tan H
Pogosyan A
Ashkan K
Cheeran B
Fitzgerald J
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Brown P

Subthalamic nucleus local field potential activity helps encode motor effort rather than force in parkinsonism.

2015.J. Neurosci., 35(15):5941-9.
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PMC4397595
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742.89 KB

2014

Tan H
Zavala B
Pogosyan A
Ashkan K
Zrinzo L
Foltynie T
Limousin P
Brown P

Human subthalamic nucleus in movement error detection and its evaluation during visuomotor adaptation.

2014.J. Neurosci., 34(50):16744-54.

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PMC4261099
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452.3 KB

2013

Tan H
Pogosyan A
Anzak A
Ashkan K
Bogdanovic M
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Brown P

Complementary roles of different oscillatory activities in the subthalamic nucleus in coding motor effort in Parkinsonism.

2013.Exp. Neurol., 248():187-95.

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PMC3972632
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1.38 MB
Tan H
Pogosyan A
Anzak A
Foltynie T
Limousin P
Zrinzo L
Ashkan K
Bogdanovic M
Green AL
Aziz TZ
Brown P

Frequency specific activity in subthalamic nucleus correlates with hand bradykinesia in Parkinson's disease.

2013.Exp. Neurol., 240():122-9.

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PMC3605592
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899.41 KB