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2017

Unit Publication
Tinkhauser G
Brown P
Pogosyan A
Schuepbach M
Pollo C
Debove I

Patent Granted: Method and system for optimisation of DBS programming

2017. WO/2017/158067
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Unit Publication
Tinkhauser G
Pogosyan A
Tan H
Herz DM
Kühn AA
Brown P

Beta burst dynamics in Parkinson's disease OFF and ON dopaminergic medication.

2017. Brain, 140(11):2968-2981.
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PMC5667742
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998.05 KB
Unit Publication
Steiner LA
Neumann WJ
Staub-Bartelt F
Herz DM
Tan H
Pogosyan A
Kühn AA
Brown P

Subthalamic beta dynamics mirror Parkinsonian bradykinesia months after neurostimulator implantation.

2017.Mov. Disord., 32(8):1183-1190.

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PMC5575541
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423.21 KB
Unit Publication
Fischer P
Pogosyan A
Herz DM
Cheeran B
Green AL
Fitzgerald J
Aziz TZ
Hyam J
Little S
Foltynie T
Limousin P
Zrinzo L
Brown P
Tan H

Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition.

2017. eLife, 6:e23947
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PMC5526662
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2.83 MB
Unit Publication
Fischer P
Pogosyan A
Cheeran B
Green AL
Aziz TZ
Hyam J
Little S
Foltynie T
Limousin P
Zrinzo L
Hariz M
Samuel M
Ashkan K
Brown P
Tan H

Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force.

2017. Exp. Neurol., 293():53-61.
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PMC5429975
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1.7 MB
Unit Publication
Tinkhauser G
Pogosyan A
Little S
Beudel M
Herz DM
Tan H
Brown P

The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease.

2017. Brain, 140(4):1053-1067.
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PMC5382944
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928.26 KB
Unit Publication
Cagnan H
Pedrosa D
Little S
Pogosyan A
Cheeran B
Aziz TZ
Green AL
Fitzgerald J
Foltynie T
Limousin P
Zrinzo L
Hariz M
Friston KJ
Denison T
Brown P

Stimulating at the right time: phase-specific deep brain stimulation.

2017. Brain, 140(1):132-145.
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PMC5226063
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727.64 KB

2016

Unit Publication
Fischer P
Tan H
Pogosyan A
Brown P

High post-movement parietal low-beta power during rhythmic tapping facilitates performance in a stop task.

2016.Eur. J. Neurosci., 44(5):2202-13.

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PMC5014120
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4.05 MB
Unit Publication
Tan H
Pogosyan A
Ashkan K
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Hariz M
Brown P

Decoding gripping force based on local field potentials recorded from subthalamic nucleus in humans.

2016. eLife;5:e19089.
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PMC5148608
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10.08 MB
Unit Publication
Little S
Tripoliti E
Beudel M
Pogosyan A
Cagnan H
Herz DM
Bestmann S
Aziz TZ
Cheeran B
Zrinzo L
Hariz M
Hyam J
Limousin P
Foltynie T
Brown P

Adaptive deep brain stimulation for Parkinson's disease demonstrates reduced speech side effects compared to conventional stimulation in the acute setting.

2016.J. Neurol. Neurosurg. Psychiatry, 87(12):1388-1389.
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PMC5136720
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619.27 KB
Unit Publication
Little S
Beudel M
Zrinzo L
Foltynie T
Limousin P
Hariz M
Neal S
Cheeran B
Cagnan H
Gratwicke J
Aziz TZ
Pogosyan A
Brown P

Bilateral adaptive deep brain stimulation is effective in Parkinson's disease.

2016.J. Neurol. Neurosurg. Psychiatry, 87(7):717-21.
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PMC4941128
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651.81 KB
Unit Publication
Guerra A
Pogosyan A
Nowak M
Tan H
Ferreri F
Di Lazzaro V
Brown P

Phase Dependency of the Human Primary Motor Cortex and Cholinergic Inhibition Cancelation During Beta tACS.

2016.Cereb. Cortex, 26(10):3977-90.

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PMC5028010
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727.73 KB

2015

Unit Publication
Beudel M
Little S
Pogosyan A
Ashkan K
Foltynie T
Limousin P
Zrinzo L
Hariz M
Bogdanovic M
Cheeran B
Green AL
Aziz TZ
Thevathasan W
Brown P

Tremor Reduction by Deep Brain Stimulation Is Associated With Gamma Power Suppression in Parkinson's Disease.

2015.Neuromodulation, 18(5):349-54.
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PMC4829100
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382.1 KB
Unit Publication
Tan H
Pogosyan A
Ashkan K
Cheeran B
Fitzgerald J
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Brown P

Subthalamic nucleus local field potential activity helps encode motor effort rather than force in parkinsonism.

2015.J. Neurosci., 35(15):5941-9.
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PMC4397595
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742.89 KB
Mehta AR
Pogosyan A
Brown P
Brittain JS

Montage matters: the influence of transcranial alternating current stimulation on human physiological tremor.

2015. Brain Stimul, 8(2): 260-8.
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PMC4319690
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1.44 MB

2014

Tan H
Zavala B
Pogosyan A
Ashkan K
Zrinzo L
Foltynie T
Limousin P
Brown P

Human subthalamic nucleus in movement error detection and its evaluation during visuomotor adaptation.

2014.J. Neurosci., 34(50):16744-54.

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PMC4261099
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452.3 KB

2013

Tan H
Pogosyan A
Anzak A
Ashkan K
Bogdanovic M
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Brown P

Complementary roles of different oscillatory activities in the subthalamic nucleus in coding motor effort in Parkinsonism.

2013.Exp. Neurol., 248():187-95.

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PMC3972632
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1.38 MB
Tan H
Pogosyan A
Anzak A
Foltynie T
Limousin P
Zrinzo L
Ashkan K
Bogdanovic M
Green AL
Aziz TZ
Brown P

Frequency specific activity in subthalamic nucleus correlates with hand bradykinesia in Parkinson's disease.

2013.Exp. Neurol., 240():122-9.

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PMC3605592
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899.41 KB
Little S
Pogosyan A
Neal S
Zavala B
Zrinzo L
Hariz M
Foltynie T
Limousin P
Ashkan K
Fitzgerald J
Green AL
Aziz TZ
Brown P

Adaptive deep brain stimulation in advanced Parkinson disease.

2013.Ann. Neurol., 74(3):449-57.
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PMC3886292
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417.36 KB

2012

Thevathasan W
Pogosyan A
Hyam J
Jenkinson N
Foltynie T
Limousin P
Bogdanovic M
Zrinzo L
Green AL
Aziz TZ
Brown P

Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism.

2012.Brain, 135(Pt 1):148-60.

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PMC3267984
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522.96 KB
Little S
Pogosyan A
Kühn AA
Brown P

β band stability over time correlates with Parkinsonian rigidity and bradykinesia.

2012.Exp. Neurol., 236(2):383-8.

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PMC3400051
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561.94 KB
Little S
Joundi RA
Tan H
Pogosyan A
Forrow B
Joint C
Green AL
Aziz TZ
Brown P

A torque-based method demonstrates increased rigidity in Parkinson's disease during low-frequency stimulation.

2012.Exp Brain Res, 219(4):499-506.

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PMC3366185
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359.59 KB
Anzak A
Tan H
Pogosyan A
Foltynie T
Limousin P
Zrinzo L
Hariz M
Ashkan K
Bogdanovic M
Green AL
Aziz TZ
Brown P

Subthalamic nucleus activity optimizes maximal effort motor responses in Parkinson's disease.

2012.Brain, 135(Pt 9):2766-78.

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PMC3437023
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774.5 KB

2011

Thevathasan W
Pogosyan A
Hyam J
Jenkinson N
Bogdanovic M
Coyne TJ
Silburn PA
Aziz TZ
Brown P

A block to pre-prepared movement in gait freezing, relieved by pedunculopontine nucleus stimulation.

2011.Brain, 134(Pt 7):2085-95.

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PMC3122373
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308.3 KB
Eusebio A
Thevathasan W
Doyle Gaynor L
Pogosyan A
Bye E
Foltynie T
Zrinzo L
Ashkan K
Aziz TZ
Brown P

Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.

2011.J. Neurol. Neurosurg. Psychiatry, 82(5):569-73.

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PMC3072048
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276.52 KB