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A photo of Hayriye Cagnan, Robert Toth and Nick Ramsey

Our congratulations go to Unit D.Phil. student Robert Toth for successfully defending his doctoral thesis, entitled “Translational pipelines for closed-loop neuromodulation”, in his viva voce examination on 24th October 2023.

Roberts’s viva examiners were Professor Nick Ramsey (University of Utrecht, Netherlands) and Professor Hayriye Cagnan (University of Oxford).

Robert was supervised by Professor Andrew Sharott and Professor Tim Denison at the Unit.

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Portrait photo of Ashwini Oswal

We are delighted to announce that Dr Ashwini Oswal is today taking up his new role as Group Leader at the Unit.

Ashwini is well known to Unit members, having already collaborated with several groups over the last 5 years on research defining the neuronal network effects of Deep Brain Stimulation used to treat Parkinson’s and other movement disorders. Ashwini was recently awarded an MRC Clinician Scientist Fellowship, which he will use to make the transition to independent investigator and lead his own research team. The focus of Ashwini's new research programme funded by the Medical Research Council is to provide an understanding of how time-resolved activity within brain networks can contribute to the cognitive and motor symptoms of Parkinson’s disease. The new insights gained will be used to inform improved brain stimulation approaches for therapy.

Unit Interim Director Professor Peter Magill commented: “We are thrilled that Ash has chosen to start his independent research programme at the Unit. Ash’s research vision is exceptionally well aligned with our discovery and translational science portfolios and, as a clinically-active healthcare professional, he brings distinctive expertise in neurology to the Unit. We look forward to working in close collaboration with Ash during his Fellowship.”

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A photo of Professor Huiling Tan

Many congratulations to Unit Group Leader Huiling Tan on being awarded the title of Professor of Human Electrophysiology and Neuromodulation by the University of Oxford.

Titles of Full Professor are conferred annually in recognition of an individual’s significant influence on their field of study, as well as their track records in teaching and academic citizenship.

Unit Interim Director Professor Peter Magill commented “I am delighted that Huiling’s many achievements have been recognised by the University in this way. Huiling’s studies of the neuronal dynamics underlying purposeful movement, and her development and use of brain-computer interfaces, are pioneering and have major implications for improving clinical therapies for brain disorders. Together with other colleagues at the Unit, I offer warmest congratulations to Huiling on receiving this well-deserved accolade.”

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Portrait photo of Ben Edwards

We are pleased to welcome Mr Ben Edwards to the Unit as a Research Assistant and Lab Manager in the Magill Group.

Ben graduated from Oxford Brookes University with a B.Sc. (Hons.) in Biochemistry in 2002. He then joined the MRC Functional Genomics Unit as a Research Assistant working on invertebrate models of Spinal Muscular Atrophy. Ben then moved to the lab of Professor Dame Kay Davies in Oxford as a Research Assistant/Lab Manager, where he remained for the next 19 years, working on a number of projects including those using mouse models of ataxia, Amyotrophic Lateral Sclerosis and schizophrenia. Ben’s research experience includes behavioural studies, molecular biology, epifluorescence and confocal microscopy. Ben was also part of a team that used in vitro screening and in vivo preclinical studies to investigate utrophin modulation therapies in Duchenne Muscular Dystrophy.

Here in the Unit, Ben will provides specialised research support to a number of projects in the Magill Group.

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Portrait photo of Ioana Grigoras

Our congratulations go to Unit D.Phil. student Ioana Grigoras for successfully defending her doctoral thesis, entitled “Investigating the role of inhibition in human motor learning”, in her viva voce examination on 5th August 2022.

Ioana’s viva examiners were Professor Ulf Ziemann (University of Tübingen, Germany) and Professor Matthew Rushworth (University of Oxford). The viva took place remotely via digital conferencing.

Ioana was supervised by Professor Charlotte Stagg (MRC BNDU) and Professor Catherine Harmer (Department of Psychiatry).

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Portrait photos of Charlotte Collingwood (left) and Vivienne Collins (right)

Congratulations to Unit student Charlotte Collingwood and Unit Administrator Dr Vivienne Collins on co-winning the Director’s Award for Public Engagement for 2022.

The Award recognises and celebrates the exemplary contributions of individuals or a small collective to the Unit’s extensive Outreach programme. The Award is given annually (this being the seventh occasion), on the basis of nominations made by Unit members.

Charlotte and Vivienne received their Awards from Unit Interim Director Professor Peter Magill at a special ceremony held at the Unit’s biannual Science Day.

Professor Magill commented “It gives us all great pleasure to reward Charlotte and Viv in this way. Charlotte has shown great enthusiasm and personal initiative in public engagement in her first year as a D.Phil. student here. Charlotte has formed new partnerships with outreach initiatives, and her podcasting skills are to be admired! Viv has played key roles in devising and delivering the Unit’s public engagement activities over the last 7 years, and the success of these activities stem from Viv’s dedication, planning and logistics skills. Viv’s colleagues clearly value her organisational brilliance and the outstanding support that she gives them.”

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A group photo of attendees at the Unit’s Science Day in summer 2022.

The Unit held its fourteenth Science Day on Friday 24th June 2022. Unpublished work and future research projects were at the centre of discussion, and Unit members and visitors eagerly took the opportunity to provide the informal constructive feedback that is essential for fostering collaborative working and team science.

There were 9 short research talks and 19 poster presentations, most of which were given by the Unit’s early-career scientists. Attendees were also treated to a Keynote Lecture from Dr Marc Aurel Busche of the UK Dementia Research Institute, in which he gave a discerning account of the impact of amyloid protein on neuronal circuit function.

Unit Interim Director Professor Peter Magill commented: “It was a great pleasure to hold our first in-person Science Day since late 2019. Unit members were energised by the chance to meet and exchange ideas under the same roof, and it was exciting to see how the work of the Unit’s students and postdoctoral staff is revealing important new insights into brain function and dysfunction.”

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Photograph of Dr Helen Barron

Many congratulations to Unit scientist Dr Helen Barron on being awarded a UKRI Future Leaders Fellowship.

UKRI Future Leaders Fellowships support talented early-career researchers to deliver ambitious and innovative programmes of research over several years. Helen will take up her Fellowship in June 2022, and will establish and lead her own research team across the MRC Brain Network Dynamics Unit and the Wellcome Centre for Integrative Neuroimaging, both of which are hosted by the Nuffield Department for Clinical Neurosciences.

Over the last few years, Helen has worked as a Postdoctoral Neuroscientist in Professor David Dupret’s Group in the Unit, where she has used a cross-species approach to uncover cell- and circuit-level mechanisms of memory in the brain. The goal of Helen’s new research programme funded by UKRI is to establish the specialized biological mechanisms that gate and control selective memory recall and explain why disturbances in memory gating may underpin core symptoms in neuropsychiatric disease.

Unit Interim Director Professor Peter Magill commented: “We are thrilled for Helen. She is an outstanding researcher, and a valued colleague and collaborator. Helen’s research vision brilliantly complements the Unit’s discovery and translational science portfolios, and we look forward to working with Helen during her Fellowship. Helen’s success provides another ringing endorsement of the Unit’s commitment to excellence in the research training and career development of its membership.”

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Protrait photo of Hayriye Cagnan

We are delighted to announce that Unit Group Leader Associate Professor Hayriye Cagnan has been selected to join this year’s SUSTAIN programme organised by The Academy of Medical Sciences.

SUSTAIN is a year-long programme offering interactive skills training and career development sessions, tailored mentoring and the chance to network with research leaders, all with a view to enabling female researchers to thrive in their independent research careers.

Hayriye commented, “I am thrilled to be part of this programme and to learn from previous generations who navigated similar challenges.”

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Cartoon of a person standing next to desk with a computer on it. The person has a brain implant that is communicating with the computer and is responding to and guiding the person’s arm movements.

We are delighted to announce that the MRC Brain Network Dynamics Unit is set to play key roles in delivering on two new EPSRC/MRC-funded Network Plus grants that are designed to build capability for responsible research across a breadth of neurotechnologies.

The first of the new networks, which is focused on meeting the challenges presented by closed-loop interactions between brains and machines, will see the Unit forming new collaborations with researchers based at the University of Newcastle, the University of Cambridge, Imperial College London, and the University of Manchester. Unit Group Leader Associate Professor Andrew Sharott will lead the Unit’s contribution to this new research network.

The second network, which is focused on addressing the challenges of developing minimally-invasive treatments for brain disorders, will see the Unit forming new collaborations with researchers based at Imperial College London, the University of Nottingham, and the University of Edinburgh. Unit Group Leader Associate Professor Hayriye Cagnan will lead the Unit’s contribution to this new research network.

Each of the new networks will also involve other Unit Groups, and will connect the academic teams with industry, research charities, the NHS, and patient groups.

Unit Interim Director Professor Peter Magill commented “This is a great opportunity for Andrew, Hayriye and Unit colleagues to form new interdisciplinary research communities and facilitate knowledge transfer and exchange across sectors. The networks are well positioned to explore the full potential of neurotechnologies for advancing discovery and translational research.”