Patent Application: Method and system for optimisation of DBS programming

Tinkhauser G
Brown P
Pogosyan A
Schuepbach M
Pollo C
Debove I
Scientific Abstract

A method and system are described for, based upon a plurality of previously-acquired directional LFP signals measured in a plurality of different directions at a directional sensor lead located in a predetermined region of a patient's brain, determining optimised patient-specific programming parameters for programming a directional stimulation lead with parameters for stimulating the said region. The method comprises a first step of determining, over at least one predetermined frequency range, a power-frequency variation curve of each of the directional LFP signals, a second step of identifying frequency peaks in the power- frequency variation curves, a third step of detecting one of the identified frequency peaks at which a maximum difference in signal power between the directional LFP signals occurs, and a fourth step of calculating a plurality of directional stimulation weighting factors on the basis of the relative signal powers of the directional LFP signals at the detected frequency peak.

flow chart
2017. WO/2017/158067
Related Content
di Biase L, Brittain JS, Brown P, Di Lazzaro V, Shah SA
2018. WO/2018/134579
Deli A, Denison T, Green AL
2022. WO/2022/200814
Weerasinghe G, Bogacz R
2022. WO/2022/029445
Denison T, Rogers DJ, Memarian Sorkhabi M
2021. WO/2021/176219