Patent Application: Neural source localisation for optimisation of deep brain stimulation

There is provided a method for determining a location of a source of neural activity signals within a brain. The method comprises measuring electrical signals from respective contacts of a plurality of contacts located at known relative positions within the brain, processing the electrical signals to detect neural activity signals in the electrical signals from the respective contacts, determining timings of the detected neural activity signals, and determining the location of the source of neural activity within the brain relative to the plurality of contacts by fitting a source model to the timings relative to each other, wherein the source model models an arrangement of the source of the neural activity signals and models the neural activity signals as travelling waves that propagate through the brain. The location of the source of neural activity can be used to guide optimal delivery of deep brain stimulation.