Colin McNamara wins WT Sir Henry Wellcome Postdoctoral Fellowship

Congratulations to Unit scientist Dr Colin McNamara who has been awarded a prestigious Sir Henry Wellcome Postdoctoral Fellowship by the Wellcome Trust in support of his new research project entitled “Closing the loop on neuronal oscillations: Motor networks take centre stage”.

This Fellowship scheme offers recently qualified postdoctoral researchers the opportunity to start independent research careers, working in some of the best research environments in the world.

Colin will pursue his 4-year research project in the Unit under the sponsorship of Programme Leader Dr Andrew Sharott, as well as at Imperial College London in collaboration with Dr Timothy Constandinou. Colin will also be mentored by Professor Pascal Fries of the Ernst Strüngmann Institute, Germany.

Colin originally joined the Unit to pursue his D.Phil. studies in Dr David Dupret’s Group, where he investigated the influence of dopamine on hippocampal circuit dynamics and memory formation.  Since graduating, Colin has been working as a Postdoctoral Neuroscientist in Dr Sharott’s Group in the Unit.

Unit Deputy Director Professor Peter Magill commented “We are thrilled for Colin. He is an exceptional scientist, outstanding collaborator, and a valued colleague. Colin’s new Fellowship is well deserved, and is a fitting testament to the culture of research training and career development that we have established at the Unit.”

A warm welcome to Chien-Hung

We are pleased to welcome Dr Chien-Hung Yeh to the Unit as a Postdoctoral Research Fellow in Professor Peter Brown’s Group.

Chien-Hung graduated from the National Central University, Taiwan, with a D.Phil. in Engineering. As part of Chien-Hung’s D.Phil. degree, he completed his thesis at the Research Center for Adaptive Data Analysis, where he used nonlinear approaches to analyze physical and biological signals, and developed effective biomarkers for clinical use. Thereafter, Chien-Hung continued his research at Harvard Medical School and Brigham and Women's Hospital, USA, working on the existence of spurious cross-frequency coupling in nonstationary and nonlinear signals, and identifying seizure dynamics in patients and circadian dynamics in animal models. After that, he worked with Dr Chiung-Chu Chen in Taiwan on oscillatory activity in the subthalamic nucleus, with special emphasis on gait disturbance.

In 2017, Chien-Hung was awarded a scholarship from the Postdoctoral Research Abroad Program in Taiwan to join the Unit. Chien-Hung will continue to research human gait, in collaboration with Dr Chiung-Chu Chen in Taiwan, as well as with Petra Fisher, Huiling Tan and Peter Brown in the Unit.

After the viva: (from left to right) a proud supervisor, a satisfied External Examiner, the happy student, a second satisfied Examiner, and another proud supervisor.

Our congratulations go to Unit D.Phil. student Petra Fischer for successfully defending her doctoral thesis, entitled "Neuronal dynamics of flexible motor control in the human subthalamic nucleus and cortex", in her viva voce examination on 6th November 2017.

Petra’s examiners were Dr Robert Schmidt (Department of Psychology, University of Sheffield) and Associate Professor Mark Stokes (Departments of Psychiatry and Experimental Psychology, University of Oxford).

Petra was supervised by Professor Peter Brown and Dr Huiling Tan.

Dr Gerd Tinkhauser

Congratulations to Unit scientist Dr Gerd Tinkhauser who has been awarded a prestigious grant from the Swiss Parkinson Association in support of his research project entitled “Electrophysiological recordings to optimise deep brain stimulation for Parkinson’s disease”. This project is a collaboration between the Unit and the Department of Neurology and Neurosurgery, University Hospital Bern, Switzerland.

Gerd joined the Unit after receiving a Research Training Fellowship from the European Academy of Neurology, and has already produced encouraging results for his new project.

A warm welcome to Julien

We are pleased to welcome Dr Julien Carponcy to the Unit as a Postdoctoral Neuroscientist in the Magill Group.

Julien originally graduated with a M.Sc. in Neurosciences, Behaviour and Cognition from the University of Toulouse, France. During Julien’s undergraduate studies, he completed two research internships in Toulouse, working on the involvement of hippocampal subregions in spatial and contextual memory. As part of a third research internship in Seville, Spain, Julien investigated the synchronization of brain oscillations within the limbic network during instrumental and observational learning. Julien then completed his Ph.D. at the Lyon Neuroscience Research Center, France, where he used behavioural tasks and in vivo electrophysiology to study the effects of different sleep stages on memory and synaptic plasticity.

Here in the Unit, Julien will be defining the functional organisation of the external globus pallidus, using a combination of in vivo electrophysiological recordings, cell-type-selective manipulations (optogenetics), and behavioural analyses, as well as ex vivo neuroanatomy.

A warm welcome to Carolina

We are pleased to welcome Carolina Reis to the Unit as an MRC-funded D.Phil. student in Professor Peter Brown’s Group and Dr Andrew Sharott’s Group.

Carolina originally graduated from the Instituto Politecnico do Porto, Portugal, with a B.Sc. in Neurophysiology. As part of Carolina’s B.Sc. degree, she completed a research project at King’s College Hospital, where she used a combination of electrical stimulation and intracranial recordings to explore the neuronal mechanisms underlying seizure onsets. Subsequently, Carolina obtained an M.Res. at University College London, where she worked with Associate Unit Member Dr Hayriye Cagnan on biophysical models of cortico-thalamic interactions describing transient beta oscillations in experimental Parkinsonism.

In 2017, Carolina secured an MRC Industrial Strategy Studentship and joined the Unit. During her D.Phil. studies, Carolina will be working to optimise phase-specific Deep Brain Stimulation for conditions like Essential Tremor. Carolina will be working closely with Dr Hayriye Cagnan, Dr Andrew Sharott and Professor Peter Brown in the Unit, as well as with Dr Timothy Denison (VP of Research and Core Technology at Medtronic).

A warm welcome to Moritz

We are pleased to welcome Moritz Möller to the Unit as an MRC-funded D.Phil. student in Rafal Bogacz’s Group.

Moritz originally graduated with a B.Sc. in Physics from the Friedrich Alexander University in Erlangen, Germany, where he studied the generation of gravitational waves in a novel, post-Einsteinian theory of gravity. In 2017, Moritz completed a Master of Advanced Study (MA.St.) in Applied Mathematics at the University of Cambridge, from where he graduated with distinction. Whilst in Cambridge, Moritz wrote an essay on deep reinforcement learning, which sparked his interest in the mathematics of learning and decision making in the brain.

During Moritz’s D.Phil. thesis work in the Unit, we will pursue his interests in the mathematical formulation of cognition and learning. His research will be focused on decision processes in the basal ganglia, and aims to unify reinforcement learning with the drift-diffusion model.

Welcome back Charlie

We are delighted to welcome Charlie Clarke-Williams back to the Unit as an MRC-funded D.Phil. student in the Dupret Group.

Charlie originally graduated with a B.A. in Neuroscience from the University of Oxford, during which he undertook a highly successful Final Honours School research project in the Unit under the supervision of Dr David Dupret. Charlie then completed an M.Res. degree at the University of Bristol, where he investigated the relationship between addiction and emotional disorders.

Charlie’s new thesis research in the Unit is focused on the assessment of neuronal network dynamics underlying drug-paired memories, and how these contribute to drug-seeking behaviours.

Welcome back Roman

We are delighted to welcome Roman Rothaermel back to the Unit as a Wellcome Trust-funded D.Phil. student in the Dupret Group.

As part of Roman’s recent M.Sc. in Neuroscience studies at the University of Oxford, he worked on a research project with Unit scientists Dr Gido van de Ven and Dr David Dupret to develop an unsupervised feature extraction framework for interneuron classification.

The goal of Roman’s new thesis research is to determine how the motivational state of an animal shapes its memory consolidation and retrieval on a large-scale systems level.

Abbey and her cake explaining Deep Brain Stimulation.

Last week, Unit scientist Dr Abbey Holt showcased her research on Deep Brain Stimulation - a form of therapy for Parkinson’s - at Oxford’s Curiosity Carnival, a diverse programme of public engagement activities held across the University and wider city.

Abbey participated in the ‘Great Research Bake-Off’, skilfully meeting the challenge of communicating the essence of her research through the use of cake!

After several hours of discussion with enthusiastic members of the public, Abbey and the other contestants shared their cakes for all to enjoy.