Key Research Areas:
Functional connectivity within subcortico-cortical motor loops in disease
Functional connectivity within subcortico-cortical motor loops in health
Therapy for movement disorders
We are at the beginning of a therapeutic revolution whereby we can interact with neural dynamics from moment-to-moment as necessary to reverse or ameliorate dysfunctional brain activity. To this end we must record and interpret brain signals in real-time with sufficient temporal and spatial resolution to give nuanced control. Although electrical brain stimulation is already affording major therapeutic benefits, there is vast scope for improving and extending this to provide adaptive and tailored interventions, and for harnessing genetic advances that enable cell-type specific stimulation.