Associate Prof. Andrew Sharott

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Andrew Sharott

Associate Prof. Andrew Sharott

MRC Programme Leader

Dr. Andrew Sharott graduated in Neuroscience at the University of Nottingham in 2001. He then moved to University College London to study for his Ph.D. in Neurological Studies, with a focus on oscillations in the basal ganglia network, under the supervision of Professor Peter Brown. In 2005, Dr. Sharott moved to the University Medical Centre, Hamburg-Eppendorf (Germany), to undertake postdoctoral work with Professor Andreas Engel. As a Marie Curie Experienced Researcher in Hamburg, Dr. Sharott continued to study oscillations in the basal ganglia, including recordings from patients undergoing the implantation of deep brain stimulation electrodes for the treatment of Parkinson's disease. In summer 2009, Dr. Sharott came to Oxford as an MRC Investigator Scientist to work in the Magill Group, where his research was focused on the use of in vivo electrophysiological recording techniques to examine the role of striatal neurons in the dopamine-intact and Parkinsonian brain. In 2015, Andrew was promoted to MRC Programme Leader.

Key Research Areas
  • Network mechanisms underlying pathological oscillations in Parkinson’s disease.
  • Development of closed-loop deep brain stimulation in animal models of Parkinson’s disease .
  • Neuronal diversity and the role of interneurons in striatal microcircuits. 
neuron

A NOS-expressing striatal interneuron

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Associate Prof. Andrew Sharott

Selected Publications
Unit Publication
Sharott A
Vinciati F
Nakamura KC
Magill PJ
2017.J. Neurosci., 37(41):9977-9998.
Unit Publication
Garas FN
Shah RS
Kormann E
Doig NM
Vinciati F
Nakamura KC
Dorst MC
Smith Y
Magill PJ
Sharott A
2016. Elife;5:e16088.
Doig NM
Magill PJ
Apicella P
Bolam JP
Sharott A
2014.J. Neurosci., 34(8):3101-17.
Sharott A
Gulberti A
Zittel S
Tudor Jones AA
Fickel U
Münchau A
Köppen JA
Gerloff C
Westphal M
Buhmann C
Hamel W
Engel AK
Moll CK

2014.J. Neurosci., 34(18):6273-85.

Sharott A
Moll CK
Engler G
Denker M
Grün S
Engel AK

2009.J. Neurosci., 29(14):4571-85.