Sharp wave/ripple network oscillations and learning-associated hippocampal maps.

Csicsvari J
Dupret D
Scientific Abstract

Sharp wave/ripple (SWR, 150-250 Hz) hippocampal events have long been postulated to be involved in memory consolidation. However, more recent work has investigated SWRs that occur during active waking behaviour: findings that suggest that SWRs may also play a role in cell assembly strengthening or spatial working memory. Do such theories of SWR function apply to animal learning? This review discusses how general theories linking SWRs to memory-related function may explain circuit mechanisms related to rodent spatial learning and to the associated stabilization of new cognitive maps.


2014.Philos. Trans. R. Soc. Lond., B, Biol. Sci., 369(1635):20120528.

van de Ven GM, Trouche S, McNamara CG, Allen K, Dupret D
2016.Neuron, 92(5):968-974.
Gava GP, McHugh SB, Lefèvre L, Lopes-Dos-Santos V, Trouche S, El-Gaby M, Schultz SR, Dupret D
2021. Nat. Neurosci., 24:326–330.
Lopes-Dos-Santos V, van de Ven GM, Morley A, Trouche S, Campo-Urriza N, Dupret D
2018. Neuron, 100(4):940–952.
Möller M, Bogacz R
2019. PLoS Comput. Biol., 15(2):e1006285.