Associate Prof. Hayriye Cagnan

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Dr. Hayriye Cagnan

Associate Prof. Hayriye Cagnan

MRC Career Development Fellow

Hayriye Cagnan studied Electrical and Electronics engineering at Cornell University as a Fulbright Scholar and specialized in signal processing and biomedical engineering (2000-2004). In 2004, she was awarded a British Chevening scholarship and was accepted to the M.Sc. programme in Engineering and Physical Science in Medicine at Imperial College. Hayriye completed her Ph.D. in Neuroscience in a joint placement between the University of Amsterdam and Philips Research Laboratories in 2010. Subsequently, Hayriye joined Professor Peter Brown’s research group and worked on tremor pathophysiology. In 2015, Hayriye was awarded a MRC Skills Development Fellowship in Biomedical Informatics, and was based at the Wellcome Trust Centre for Neuroimaging at University College London.

Hayriye was awarded a MRC Career Development Award in 2018. As part of her new research programme, Hayriye is developing theoretical tools and experimental approaches to elucidate how different brain regions communicate and control behaviour in heath and disease. Taking this forward, Hayriye will explore the potential of using finely-timed stimulation to modulate brain activity for improved symptom relief with fewer side effects in Essential Tremor and Parkinson's disease. 

Key Research Areas

Hayriye's research provides theory-driven strategies for stimulation that can selectively modulate brain rhythms. 

  1. Theoretical models of disease and stimulation
  2. Dynamic Neuromodulation
  3. Remote therapy optimisation
  4. Wearable devices and remote monitoring 
Research Techniques
  1. Theoretical models (e.g. Hodgkin and Huxley, neural mass models, etc.)
  2. Biomedical imaging (e.g. EEG, Optically Pumped Magnetometers, etc.)
  3. Invasive and non-invasive brain stimulation
  4. Peripheral nerve stimulation
  5. Signal processing
Selected Publications
Unit Publication
Arruda BS
Reis C
Sermon JJ
Pogosyan A
Brown P
Cagnan H
2021. J. Neuroeng. Rehabil., 18(1):179.
Unit Publication
Cagnan H
Mallet N
Moll CK
Gulberti A
Holt AB
Westphal M
Gerloff C
Engel AK
Hamel W
Magill PJ
Brown P
Sharott A
2019. Proc. Natl. Acad. Sci. U.S.A., 116:16095-16104.
Unit Publication
Cagnan H
Denison T
McIntyre C
Brown P
2019. Nat. Biotechnol., 37(9):1024-1033.
Unit Publication
Cagnan H
Pedrosa D
Little S
Pogosyan A
Cheeran B
Aziz TZ
Green AL
Fitzgerald J
Foltynie T
Limousin P
Zrinzo L
Hariz M
Friston KJ
Denison T
Brown P
2017. Brain, 140(1):132-145.
Cagnan H
Little S
Foltynie T
Limousin P
Zrinzo L
Hariz M
Cheeran B
Fitzgerald J
Green AL
Aziz TZ
Brown P

2014.Brain, 137(Pt 12):3223-34.