Sharp wave/ripple network oscillations and learning-associated hippocampal maps.

Csicsvari J
Scientific Abstract

Sharp wave/ripple (SWR, 150-250 Hz) hippocampal events have long been postulated to be involved in memory consolidation. However, more recent work has investigated SWRs that occur during active waking behaviour: findings that suggest that SWRs may also play a role in cell assembly strengthening or spatial working memory. Do such theories of SWR function apply to animal learning? This review discusses how general theories linking SWRs to memory-related function may explain circuit mechanisms related to rodent spatial learning and to the associated stabilization of new cognitive maps.

Citation

2014.Philos. Trans. R. Soc. Lond., B, Biol. Sci., 369(1635):20120528.

Related Content
Paper
Author
Lefèvre L
Trouche S
El-Gaby M
Schultz SR

2021. Nat Neurosci, 24(3):326-330.

Paper
Author
Liebana S
Laffere A
Toschi C
Schilling L
Moretti J
Podlaski J
Fritsche M
Zatka-Haas P
Li Y
Saxe A
Lak A

2025. Cell, 188(14):3789-3805.e33.