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2022

Unit Publication
Shah SA
Nguyen TAK
Petermann K
Khawaldeh S
Debove I
Shah SA
Torrecillos F
Tan H
Pogosyan A
Lachenmayer ML
Michelis J
Brown P
Pollo C
Krack P
Nowacki A
Tinkhauser G

Combining Multimodal Biomarkers to Guide Deep Brain Stimulation Programming in Parkinson Disease.

2022. Neuromodulation, Feb 23: in press.
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2.66 MB
Unit Publication
Wiest C
Torrecillos F
Tinkhauser G
Pogosyan A
Morgante F
Pereira EA
Tan H

Finely-tuned gamma oscillations: Spectral characteristics and links to dyskinesia.

2022. Exp. Neurol., 351:113999.
Free Full Text at Europe PMC
PMC7612436
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1.96 MB
Unit Publication
Khawaldeh S
Tinkhauser G
Torrecillos F
He S
Foltynie T
Limousin P
Zrinzo L
Oswal A
Quinn AJ
Vidaurre D
Tan H
Litvak V
Kühn AA
Woolrich M
Brown P

Balance between competing spectral states in subthalamic nucleus is linked to motor impairment in Parkinson's disease.

2022. Brain, 145(1):237-250.
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PMC8967096
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1.36 MB

2021

Unit Publication
Fischer P
He S
Tan H
Brown P

Patent Application: Treatment of gait impairment using deep brain stimulation

2021. WO/2021/250398
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2.35 MB
Unit Publication
He S
Deli A
Fischer P
Wiest C
Huang Y
Martin S
Khawaldeh S
Aziz TZ
Green AL
Brown P
Tan H

Gait-phase modulates alpha and beta oscillations in the pedunculopontine nucleus.

2021. J. Neurosci., 41(40):8390-8402.
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PMC8496192
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3.12 MB
Unit Publication
Huang Y
Sun B
Debarros J
Zhang C
Zhan S
Li D
Zhang C
Wang T
Huang P
Lai Y
Brown P
Cao C
Tan H

Increased theta/alpha synchrony in the habenula-prefrontal network with negative emotional stimuli in human patients.

2021. eLife, 10:e65444.
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PMC8275130
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3.64 MB
Unit Publication
He S
Baig F
Mostofi A
Pogosyan A
Debarros J
Green AL
Aziz TZ
Pereira EA
Brown P
Tan H

Closed-Loop Deep Brain Stimulation for Essential Tremor Based on Thalamic Local Field Potentials.

2021. Mov. Disord., 36(4):863-873.
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PMC7610625
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1.41 MB
Unit Publication
Wiest C
Tinkhauser G
Pogosyan A
He S
Baig F
Morgante F
Mostofi A
Pereira EA
Tan H
Brown P
Torrecillos F

Subthalamic deep brain stimulation induces finely-tuned gamma oscillations in the absence of levodopa.

2021. Neurobiol. Dis., 152:105287.
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PMC7116781
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10.76 MB

2020

Unit Publication
Debarros J
Brown P
Tan H
Denison T

Patent Application: Emulation of electrophysiological signals derived by stimulation of a body

2020. WO/2020/165591
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4.48 MB
Unit Publication
He S
Mostofi A
Syed EC
Torrecillos F
Tinkhauser G
Fischer P
Pogosyan A
Hasegawa H
Li Y
Ashkan K
Pereira EA
Brown P
Tan H

Subthalamic beta-targeted neurofeedback speeds up movement initiation but increases tremor in Parkinsonian patients.

2020. eLife, 9:e60979.
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PMC7695453
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1.9 MB
Unit Publication
Fischer P
He S
de Roquemaurel A
Akram H
Foltynie T
Limousin P
Zrinzo L
Hyam J
Cagnan H
Brown P
Tan H

Entraining stepping movements of Parkinson's patients to alternating subthalamic nucleus deep brain stimulation.

2020. J. Neurosci., 40(46):8964–8972.
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PMC7659462
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1017.91 KB
Unit Publication
Wiest C
Tinkhauser G
Pogosyan A
Bange M
Muthuraman M
Groppa S
Baig F
Mostofi A
Pereira EA
Tan H
Brown P
Torrecillos F

Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease.

2020. Neurobiol. Dis., 143:105019.
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PMC7115855
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4.15 MB
Unit Publication
Yeh CH
Al-Fatly B
Kühn AA
Meidahl AC
Tinkhauser G
Tan H
Brown P

Waveform changes with the evolution of beta bursts in the human subthalamic nucleus.

2020. Clin. Neurophysiol., 131(9):2086-2099.
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PMC7115847
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1.62 MB
Unit Publication
Debarros J
Brown P
Tan H

Patent Application: Measurement of electrophysiological signals during stimulation of a target area of a body

2020. WO/2020/070492
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4.26 MB
Unit Publication
He S
Everest-Phillips C
Clouter A
Brown P
Tan H

Neurofeedback-Linked Suppression of Cortical β Bursts Speeds Up Movement Initiation in Healthy Motor Control: A Double-Blind Sham-Controlled Study.

2020. J. Neurosci., 40(20):4021-4032.
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PMC7219286
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1.89 MB
Unit Publication
Tinkhauser G
Torrecillos F
Pogosyan A
Mostofi A
Bange M
Fischer P
Tan H
Hasegawa H
Glaser M
Muthuraman M
Groppa S
Ashkan K
Pereira EA
Brown P

The Cumulative Effect of Transient Synchrony States on Motor Performance in Parkinson's Disease.

2020. J. Neurosci., 40(7):1571-1580.

Free Full Text at Europe PMC
PMC7044725
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1.35 MB

2019

Unit Publication
Chen CC
Yeh CH
Chan HL
Chang YJ
Tu PH
Yeh CH
Lu CS
Fischer P
Tinkhauser G
Tan H
Brown P

Subthalamic nucleus oscillations correlate with vulnerability to freezing of gait in patients with Parkinson's disease.

2019. Neurobiol. Dis., 132:104605.
Free Full Text at Europe PMC
PMC6764839
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1.52 MB
Unit Publication
Lofredi R
Tan H
Neumann WJ
Yeh CH
Schneider GH
Kühn AA
Brown P

Beta bursts during continuous movements accompany the velocity decrement in Parkinson's disease patients.

2019. Neurobiol. Dis., 127:462-471.
Free Full Text at Europe PMC
PMC6520224
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1.48 MB
Unit Publication
Fischer P
Pogosyan A
Green AL
Aziz TZ
Hyam J
Foltynie T
Limousin P
Zrinzo L
Samuel M
Ashkan K
Da Lio M
De Cecco M
Fornaser A
Brown P
Tan H

Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine.

2019. Neurobiol. Dis., 127:253-263.
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PMC6517271
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1.74 MB
Unit Publication
Tan H
Debarros J
He S
Pogosyan A
Aziz TZ
Huang Y
Wang S
Timmermann L
Visser-Vandewalle V
Pedrosa D
Green AL
Brown P

Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor.

2019. Brain Stimul., 12(4):858-867.
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PMC6600875
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2.18 MB

2018

Unit Publication
Tan H
Fischer P
Shah SA
Vidaurre D
Woolrich M
Brown P

Decoding Movement States in Stepping Cycles Based on Subthalamic LFPs in Parkinsonian Patients.

2018. Conf Proc IEEE Eng Med Biol Soc, 2018:1384-1387.
Free Full Text at Europe PMC
PMC6277015
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2.51 MB
Unit Publication
Torrecillos F
Tinkhauser G
Fischer P
Green AL
Aziz TZ
Foltynie T
Limousin P
Zrinzo L
Ashkan K
Brown P
Tan H

Modulation of Beta Bursts in the Subthalamic Nucleus Predicts Motor Performance.

2018. J. Neurosci., 38(41):8905-8917.
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PMC6181312
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1.29 MB
Unit Publication
Shah SA
Tan H
Tinkhauser G
Brown P

Towards Real-Time, Continuous Decoding of Gripping Force From Deep Brain Local Field Potentials.

2018.IEEE Trans Neural Syst Rehabil Eng, 26(7):1460-1468.
Free Full Text at Europe PMC
PMC6044421
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1.13 MB
Unit Publication
Tinkhauser G
Torrecillos F
Duclos Y
Tan H
Pogosyan A
Fischer P
Carron R
Welter ML
Karachi C
Vandenberghe W
Nuttin B
Witjas T
Régis J
Azulay JP
Eusebio A
Brown P

Beta burst coupling across the motor circuit in Parkinson's disease.

2018. Neurobiol. Dis., 117(Sept):217-225.
Free Full Text at Europe PMC
PMC6054304
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1.23 MB
Unit Publication
Fischer P
Chen CC
Chang YJ
Yeh CH
Pogosyan A
Herz DM
Cheeran B
Green AL
Aziz TZ
Hyam J
Little S
Foltynie T
Limousin P
Zrinzo L
Hasegawa H
Samuel M
Ashkan K
Brown P
Tan H

Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping.

2018. J. Neurosci., 38(22):5111-5121.
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PMC5977446
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1.78 MB