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2020

Unit Publication
He S
Mostofi A
Syed EC
Torrecillos F
Tinkhauser G
Fischer P
Pogosyan A
Hasegawa H
Li Y
Ashkan K
Pereira EA
Brown P
Tan H

Subthalamic beta-targeted neurofeedback speeds up movement initiation but increases tremor in Parkinsonian patients.

2020. eLife, 9:e60979.
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PMC7695453
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1.9 MB
Unit Publication
Baaske MK
Kormann E
Holt AB
Gulberti A
McNamara CG
Pötter-Nerger M
Westphal M
Engel AK
Hamel W
Brown P
Moll CK
Sharott A

Parkinson's disease uncovers an underlying sensitivity of subthalamic nucleus neurons to beta-frequency cortical input in vivo.

2020. Neurobiol. Dis., 146:105119.
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PMC7710979
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7.35 MB
Unit Publication
Fischer P
He S
de Roquemaurel A
Akram H
Foltynie T
Limousin P
Zrinzo L
Hyam J
Cagnan H
Brown P
Tan H

Entraining stepping movements of Parkinson's patients to alternating subthalamic nucleus deep brain stimulation.

2020. J. Neurosci., 40(46):8964–8972.
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PMC7659462
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1017.91 KB
Unit Publication
Piña-Fuentes D
van Dijk JMC
van Zijl JC
Moes HR
van Laar T
Oterdoom DLM
Little S
Brown P
Beudel M

Acute effects of adaptive Deep Brain Stimulation in Parkinson's disease.

2020. Brain Stimul., 13(6):1507-1516.
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PMC7116216
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808.1 KB
Unit Publication
Wang HL
Cheng W
Rolls ET
Dai F
Gong W
Du J
Zhang WN
Wang S
Liu F
Wang J
Brown P
Feng J

Association of specific biotypes in patients with Parkinson disease and disease progression.

2020. Neurology, 95(11):e1445-e1460.
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PMC7116258
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1.73 MB
Unit Publication
Shah SA
Brown P
Gimeno H
Lin JP
McClelland VM

Application of Machine Learning Using Decision Trees for Prognosis of Deep Brain Stimulation of Globus Pallidus Internus for Children With Dystonia.

2020. Front. Neurol., 11:825.
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PMC7115974
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1.43 MB
Unit Publication
Wiest C
Tinkhauser G
Pogosyan A
Bange M
Muthuraman M
Groppa S
Baig F
Mostofi A
Pereira EA
Tan H
Brown P
Torrecillos F

Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease.

2020. Neurobiol. Dis., 143:105019.
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PMC7115855
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4.15 MB
Unit Publication
Yeh CH
Al-Fatly B
Kühn AA
Meidahl AC
Tinkhauser G
Tan H
Brown P

Waveform changes with the evolution of beta bursts in the human subthalamic nucleus.

2020. Clin. Neurophysiol., 131(9):2086-2099.
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PMC7115847
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1.62 MB
Unit Publication
Debarros J
Brown P
Tan H

Patent Application: Measurement of electrophysiological signals during stimulation of a target area of a body

2020. WO/2020/070492
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4.26 MB
Unit Publication
Little S
Brown P

Debugging adaptive deep brain stimulation for Parkinson's disease.

2020. Mov. Disord., 35(4):555-561.
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PMC7166127
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306.08 KB
Unit Publication
He S
Everest-Phillips C
Clouter A
Brown P
Tan H

Neurofeedback-Linked Suppression of Cortical β Bursts Speeds Up Movement Initiation in Healthy Motor Control: A Double-Blind Sham-Controlled Study.

2020. J. Neurosci., 40(20):4021-4032.
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PMC7219286
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1.89 MB
Unit Publication
McClelland VM
Cvetkovic Z
Lin JP
Mills KR
Brown P

Abnormal patterns of corticomuscular and intermuscular coherence in childhood dystonia.

2020. Clin. Neurophysiol., 131(4):967-977.
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PMC7083222
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1.54 MB
Unit Publication
Fischer P
Lipski WJ
Neumann WJ
Turner R
Fries P
Brown P
Richardson RM

Movement-related coupling of human subthalamic nucleus spikes to cortical gamma.

2020. eLife, 9:e51956.
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PMC7096181
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1.95 MB
Unit Publication
Tinkhauser G
Torrecillos F
Pogosyan A
Mostofi A
Bange M
Fischer P
Tan H
Hasegawa H
Glaser M
Muthuraman M
Groppa S
Ashkan K
Pereira EA
Brown P

The Cumulative Effect of Transient Synchrony States on Motor Performance in Parkinson's Disease.

2020. J. Neurosci., 40(7):1571-1580.

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PMC7044725
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1.35 MB
Unit Publication
Khawaldeh S
Tinkhauser G
Shah SA
Petermann K
Debove I
Nguyen TAK
Nowacki A
Lachenmayer ML
Schuepbach M
Pollo C
Krack P
Woolrich M
Brown P

Subthalamic nucleus activity dynamics and limb movement prediction in Parkinson's disease.

2020. Brain, 143(2):582-596.
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PMC7009471
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1.1 MB
Unit Publication
Torrecillos F
Falato E
Pogosyan A
West TO
Di Lazzaro V
Brown P

Motor cortex inputs at the optimum phase of beta cortical oscillations undergo more rapid and less variable corticospinal propagation.

2020. J. Neurosci., 40(2):369-381.
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PMC6948941
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1.78 MB

2019

Unit Publication
Chen CC
Yeh CH
Chan HL
Chang YJ
Tu PH
Yeh CH
Lu CS
Fischer P
Tinkhauser G
Tan H
Brown P

Subthalamic nucleus oscillations correlate with vulnerability to freezing of gait in patients with Parkinson's disease.

2019. Neurobiol. Dis., 132:104605.
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PMC6764839
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1.52 MB
Unit Publication
Cagnan H
Denison T
McIntyre C
Brown P

Emerging technologies for improved deep brain stimulation.

2019. Nat. Biotechnol., 37(9):1024-1033.
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PMC6877347
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2.75 MB
Unit Publication
Weerasinghe G
Duchet B
Cagnan H
Brown P
Bick C
Bogacz R

Predicting the effects of deep brain stimulation using a reduced coupled oscillator model.

2019. PLoS Comput. Biol., 15(8):e1006575.
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PMC6701819
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2.63 MB
Unit Publication
Cagnan H
Mallet N
Moll CK
Gulberti A
Holt AB
Westphal M
Gerloff C
Engel AK
Hamel W
Magill PJ
Brown P
Sharott A

Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network.

2019. Proc. Natl. Acad. Sci. U.S.A., 116:16095-16104.
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PMC6690030
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1.59 MB
Unit Publication
Lofredi R
Tan H
Neumann WJ
Yeh CH
Schneider GH
Kühn AA
Brown P

Beta bursts during continuous movements accompany the velocity decrement in Parkinson's disease patients.

2019. Neurobiol. Dis., 127:462-471.
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PMC6520224
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1.48 MB
Unit Publication
Fischer P
Pogosyan A
Green AL
Aziz TZ
Hyam J
Foltynie T
Limousin P
Zrinzo L
Samuel M
Ashkan K
Da Lio M
De Cecco M
Fornaser A
Brown P
Tan H

Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine.

2019. Neurobiol. Dis., 127:253-263.
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PMC6517271
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1.74 MB
Unit Publication
Tan H
Debarros J
He S
Pogosyan A
Aziz TZ
Huang Y
Wang S
Timmermann L
Visser-Vandewalle V
Pedrosa D
Green AL
Brown P

Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor.

2019. Brain Stimul., 12(4):858-867.
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PMC6600875
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2.18 MB
Unit Publication
Meidahl AC
Moll CK
van Wijk B
Gulberti A
Tinkhauser G
Westphal M
Engel AK
Hamel W
Brown P
Sharott A

Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients.

2019. Neurobiol. Dis., 127:101-113.
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PMC6545172
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2.71 MB
Unit Publication
Holt AB
Kormann E
Gulberti A
Pötter-Nerger M
McNamara CG
Cagnan H
Baaske MK
Little S
Köppen JA
Buhmann C
Westphal M
Gerloff C
Engel AK
Brown P
Hamel W
Moll CK
Sharott A

Phase-Dependent Suppression of Beta Oscillations in Parkinson's Disease Patients.

2019. J. Neurosci., 39(6):1119-1134.
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PMC6363933
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3.34 MB