Dr. Chien-Hung Yeh
Dr. Chien-Hung Yeh
Chien-Hung graduated with a D.Phil. in Engineering from the National Central University, Taiwan, in 2016. During Chien-Hung’s D.Phil. degree, he worked at the Research Center for Adaptive Data Analysis, where he used nonlinear approaches to analyze physical and biological signals, and developed effective biomarkers for clinical use. For example, he demonstrated the feasibility of using indexes based on phase-amplitude coupling to quantify spasticity in hemiplegia stroke patients using less than three swinging cycles in the pendulum test. He also investigated the interaction between heart rate variability and sleep EEG using adaptive data decomposition methods and fractal analysis. Subsequently, he had the opportunity to join Harvard Medical School and Brigham and Women's Hospital in the USA. There, he described how nonstationary, nonlinear oscillatory signals may produce spurious cross-frequency coupling. He also used nonlinear analytical approaches to investigate seizure dynamics from human electrocorticograms, and circadian dynamics in animal locomotor activity. After that, he worked with Dr Chiung-Chu Chen in Taiwan on oscillatory activity in the subthalamic nucleus, with a special emphasis on gait disturbanced. In 2017, Chien-Hung was awarded a scholarship from the Postdoctoral Research Abroad Program in Taiwan to join the Unit.
Chien-Hung’s research is focused on understanding the relationship between neuronal activity and network dynamic states on different time scales. Working in collaboration with Dr Chiung-Chu Chen in Taiwan, as well as with Petra Fisher, Huiling Tan and Peter Brown in the Unit, Chien-Hung will be exploring oscillatory activity in the subthalamic nucleus and its relationship to gait disturbance in Parkinsonism.